Origin of life models based on “energized assemblages of building blocks” are untenable in principle. This is fundamentally a consequence of the fact that any living system is in a physical state that is extremely far from equilibrium, a condition it must itself build and sustain. This in turn requires that it carries out all of its molecular transformations–obligatorily those that convert, and thereby create, disequilibria–using case‐specific mechanochemical macromolecular machines. Mass‐action solution chemistry is quite unable to do this. We argue (...) in Part 2 of this series that this inherent dependence of life on disequilibria‐converting macromolecular machines is also an obligatory requirement for life at its emergence. Therefore, life must have been launched by the operation of abiotic macromolecular machines driven by abiotic, but specifically “life‐like”, disequilibria, coopted from mineral precipitates that are chemically and physically active. Models grounded in “chemistry‐in‐a‐bag” ideas, however energized, should not be considered. (shrink)

We argued in Part 1 of this series that because all living systems are extremely far‐from‐equilibrium dynamic confections of matter, they must necessarily be driven to that state by the conversion of chemically specific external disequilibria into specific internal disequilibria. Such conversions require task‐specific macromolecular engines. We here argue that the same is not only true of life at its emergence; it is the enabling cause of that emergence; although here the external driving disequilibria, and the conversion engines needed must (...) have been abiotic. We argue further that the initial step in life's emergence can only create an extremely simple non‐equilibrium “seed” from which all the complexity of life must then develop. We assert that this complexity develops incrementally and progressively, each step tested for value added “in flight.” And we make the case that only the submarine alkaline hydrothermal vent (AHV) model has the potential to satisfy these requirements. (shrink)

Two semantic paradoxes, the Liar and Curry’s paradox, are analysed using a newly developed conception of procedural semantics (semantics according to which the truth of propositions is determined algorithmically), whose main characteristic is its departure from methodological realism. Rather than determining pre-existing facts, procedures are constitutive of them. Of this semantics, two versions are considered: closed (where the halting of procedures is presumed) and open (without this presumption). To this end, a procedural approach to deductive reasoning is developed, based on (...) the idea of simulation. As is shown, closed semantics supports classical logic, but cannot in any straightforward way accommodate the concept of truth. In open semantics, where paradoxical propositions naturally ‘belong’, they cease to be paradoxical; yet, it is concluded that the natural choice—for logicians and common people alike—is to stick to closed semantics, pragmatically circumventing problematic utterances. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in (...) the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

“Between the earliest and the latest of the works included here, we have two hundred and fifty years of vigorous and adventurous philosophizing,” Monroe Beardsley writes in his Introduction to this collection. “If the modern period can be only vaguely or arbitrarily bounded, it can at least be studied, and we can ask whether any dominant themes, overall patterns of movement, or notable achievements can be found within it. This question is one that is best asked by the reader (...) after he has read, or read around in, these works.” This Modern Library Paperback Classic also includes a newly updated Bibliography. (shrink)

This second edition features a new 48-page Afterword--1980 updating Professor Beardsley's classic work.

This second edition features a new 48-page Afterword--1980 updating Professor Beardsley's classic work.

The global health crisis in non-communicable diseases (NCDs) reveals a deep global health inequity that lies at the heart of global justice concerns. Mirroring the HIV/AIDS epidemic, NCDs bring into stark relief once more the human consequences of trade policies that reinforce global inequities in treatment access. Recognising distributive justice issues in access to medicines for their populations, World Trade Organisation (WTO) members confirmed the primacy of access to medicines for all in trade and public health in the landmark Doha (...) Declaration on the TRIPS Agreement and Public Health of 2001. (shrink)

Many philosophers apparently still accept the proposition that there is such a thing as intrinsic value, i.e., that some part of the value of some things (objects, events, or states of affairs) is intrinsic value. John Dewey's attack seems not to have dislodged this proposition, for today it is seldom questioned. I propose to press the attack again, in terms that owe a great deal to Dewey, as I understand him.

"For those of us who want to know what philosophers have said about beauty and the arts, this book will be especially useful.”—The Philosophical Review At once a treatise for professionals and a guide for newcomers to the subject, ...

In writing this book I have received a considerable variety of assistance, which I am glad to acknowledge.

In writing this book I have received a considerable variety of assistance, which I am glad to acknowledge.

We explore the possibilities for elementary embeddings $j : M \to N$, where M and N are models of ZFC with the same ordinals, $M \subseteq N$, and N has access to large pieces of j. We construct commuting systems of such maps between countable transitive models that are isomorphic to various canonical linear and partial orders, including the real line ${\mathbb R}$.

A morally perfect God necessarily desires that all rational agents behave morally. An omnipotent and omniscient God has the power and knowledge to ensure that all rational agents have sufficient moral knowledge to do what morality requires. So, if God exists, there are no rational moral agents who lack sufficient moral knowledge to act morally. However, there has been a wide range of moral agents who, without blame, have lacked the moral knowledge to behave morally. Therefore, God does not exist. (...) The preceding argument from non-blameable moral ignorance of our fundamental moral obligations is resistant to some of the standard theistic responses to the problem of evil and divine hiddenness. Moreover, some of the standard theistic responses to the traditional arguments for God’s non-existence lend support to the argument from blameless moral ignorance. (shrink)

Essays explore the philosophy of art, the definition of a work of art, the aims of art criticism, and the nature of creativity.